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KMID : 1030220150160020101
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Journal of Korean Diabetes
2015 Volume.16 No. 2 p.101 ~ p.107
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Diagnosis and Glycemic Control of Type 1 Diabetes
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Kim Jae-Hyun
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Abstract
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Type 1 diabetes mellitus (T1DM) is characterized by an immune-mediated beta-cell destruction that causes lifelong insulin dependency. Diagnosis of diabetes is based on fasting glucose, 2-h plasma glucose value after a 75-g oral glucose tolerance test, or hemoglobin A1c (HbA1c) levels. Differentiation between type 1 and 2 diabetes is important for both education and treatment. Diabetes-associated autoantibodies, c-peptide and clinical characteristics should be considered to confirm the diagnosis of T1DM. A single HbA1c target of < 7.5% across all pediatric age groups is recommended. In nonpregnant adults, a reasonable HbA1c goal is < 7.0% to reduce the incidence of microvascular complications of T1DM. Glycemic targets should be individualized according to lifestyle, psychosocial and medical circumstances.
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KEYWORD
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Diagnosis, Glycemic target, Type 1 diabetes
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